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Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways

The prostaglandin and leukotriene families of lipid mediators are formed via two distinct biosynthetic pathways that are initiated by the oxygenation of arachidonic acid by either cyclooxygenase-2 (COX-2) or 5-lipoxygenase (5-LOX), respectively. The 5-LOX product 5S-hydroxyeicosatetraenoic acid, how...

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Bibliografiset tiedot
Päätekijät: Griesser, Markus, Suzuki, Takashi, Tejera, Noemi, Mont, Stacey, Boeglin, William E., Pozzi, Ambra, Schneider, Claus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084063/
https://ncbi.nlm.nih.gov/pubmed/21482803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019473108
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