Autoxidative and Cyclooxygenase-2 Catalyzed Transformation of the Dietary Chemopreventive Agent Curcumin

The efficacy of the diphenol curcumin as a cancer chemopreventive agent is limited by its chemical and metabolic instability. Non-enzymatic degradation has been described to yield vanillin, ferulic acid, and feruloylmethane through cleavage of the heptadienone chain connecting the phenolic rings. He...

Full description

Saved in:
Bibliographic Details
Main Authors: Griesser, Markus, Pistis, Valentina, Suzuki, Takashi, Tejera, Noemi, Pratt, Derek A., Schneider, Claus
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020718/
https://ncbi.nlm.nih.gov/pubmed/21071447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178806
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items