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Autoxidative and Cyclooxygenase-2 Catalyzed Transformation of the Dietary Chemopreventive Agent Curcumin

The efficacy of the diphenol curcumin as a cancer chemopreventive agent is limited by its chemical and metabolic instability. Non-enzymatic degradation has been described to yield vanillin, ferulic acid, and feruloylmethane through cleavage of the heptadienone chain connecting the phenolic rings. He...

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Bibliografische gegevens
Hoofdauteurs: Griesser, Markus, Pistis, Valentina, Suzuki, Takashi, Tejera, Noemi, Pratt, Derek A., Schneider, Claus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020718/
https://ncbi.nlm.nih.gov/pubmed/21071447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178806
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