Development of “plug and play” fiducial marks for structural studies of GPCR signaling complexes by single particle cryo-EM

“Universal” synthetic antibody (sAB)-based fiducial marks have been generated by customized phage display selections to facilitate the rapid structure determination of G-protein coupled receptor (GPCR) signaling complexes by single particle cryo-electron microscopy (SP cryo-EM). sABs were generated...

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Veröffentlicht in:Structure
Hauptverfasser: Dutka, Przemyslaw, Mukherjee, Somnath, Gao, Xiang, Kang, Yanyong, de Waal, Parker W., Wang, Lei, Zhuang, Youwen, Melcher, Karsten, Zhang, Cheng, Xu, H. Eric, Kossiakoff, Anthony A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297049/
https://ncbi.nlm.nih.gov/pubmed/31669042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.10.004
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