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USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9
The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for nuclear speckle factors involved in homologous recombina...
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| Опубликовано в: : | Oncogenesis |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7296013/ https://ncbi.nlm.nih.gov/pubmed/32541651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00244-4 |
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