USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9

The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for nuclear speckle factors involved in homologous recombina...

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Библиографические подробности
Опубликовано в: :Oncogenesis
Главные авторы: Matsui, Misaki, Sakasai, Ryo, Abe, Masako, Kimura, Yusuke, Kajita, Shoki, Torii, Wakana, Katsuki, Yoko, Ishiai, Masamichi, Iwabuchi, Kuniyoshi, Takata, Minoru, Nishi, Ryotaro
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296013/
https://ncbi.nlm.nih.gov/pubmed/32541651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00244-4
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