USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9

The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for nuclear speckle factors involved in homologous recombina...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogenesis
Egile Nagusiak: Matsui, Misaki, Sakasai, Ryo, Abe, Masako, Kimura, Yusuke, Kajita, Shoki, Torii, Wakana, Katsuki, Yoko, Ishiai, Masamichi, Iwabuchi, Kuniyoshi, Takata, Minoru, Nishi, Ryotaro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296013/
https://ncbi.nlm.nih.gov/pubmed/32541651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00244-4
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