USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9

The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for nuclear speckle factors involved in homologous recombina...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Matsui, Misaki, Sakasai, Ryo, Abe, Masako, Kimura, Yusuke, Kajita, Shoki, Torii, Wakana, Katsuki, Yoko, Ishiai, Masamichi, Iwabuchi, Kuniyoshi, Takata, Minoru, Nishi, Ryotaro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296013/
https://ncbi.nlm.nih.gov/pubmed/32541651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00244-4
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