USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9

The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for nuclear speckle factors involved in homologous recombina...

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Publicat a:Oncogenesis
Autors principals: Matsui, Misaki, Sakasai, Ryo, Abe, Masako, Kimura, Yusuke, Kajita, Shoki, Torii, Wakana, Katsuki, Yoko, Ishiai, Masamichi, Iwabuchi, Kuniyoshi, Takata, Minoru, Nishi, Ryotaro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296013/
https://ncbi.nlm.nih.gov/pubmed/32541651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00244-4
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