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Humanized Anti-TAG-72 for Sub-Millimeter Near-Infrared Detection of Colon Cancer in Metastatic Mouse Models

BACKGROUND: Tumor-associated glycoprotein (TAG)-72 is a pancarcinoma antigen that is overexpressed in greater than 80% of colorectal adenocarcinomas. CC49 is a TAG-72-specific antibody. The aim of the present study was to demonstrate selective imaging of colon tumors and metastases with humanized TA...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Hollandsworth, Hannah M., Amirfakhri, Siamak, Filemoni, Filemoni, Hoffman, Robert M., Molnar, Justin, Yazaki, Paul J., Bouvet, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295682/
https://ncbi.nlm.nih.gov/pubmed/32217350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2020.02.017
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