Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology

Late-Onset Alzheimer’s disease (LOAD) is a common, complex genetic disorder well-known for its heterogeneous pathology. The genetic heterogeneity underlying common, complex diseases poses a major challenge for targeted therapies and the identification of novel disease-associated variants. Case-contr...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Milind, Nikhil, Preuss, Christoph, Haber, Annat, Ananda, Guruprasad, Mukherjee, Shubhabrata, John, Cai, Shapley, Sarah, Logsdon, Benjamin A., Crane, Paul K., Carter, Gregory W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295244/
https://ncbi.nlm.nih.gov/pubmed/32492070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008775
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