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Molecular and structural characterization of disease-associated APE1 polymorphisms

Under conditions of oxidative stress, reactive oxygen species (ROS) continuously assault the structure of DNA resulting in oxidation and fragmentation of the nucleobases. When the nucleobase structure is altered, its base-pairing properties may also be altered, promoting mutations. Consequently, oxi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:DNA Repair (Amst)
Prif Awduron: Whitaker, Amy M., Stark, Wesley J., Flynn, Tony S., Freudenthal, Bret D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295089/
https://ncbi.nlm.nih.gov/pubmed/32454397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102867
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