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Base excision repair of oxidative DNA damage: from mechanism to disease

Reactive oxygen species continuously assault the structure of DNA resulting in oxidation and fragmentation of the nucleobases. Both oxidative DNA damage itself and its repair mediate the progression of many prevalent human maladies. The major pathway tasked with removal of oxidative DNA damage, and...

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Detalhes bibliográficos
Publicado no:Front Biosci (Landmark Ed)
Main Authors: Whitaker, Amy M., Schaich, Matthew A., Smith, Mallory S., Flynn, Tony S., Freudenthal, Bret. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567671/
https://ncbi.nlm.nih.gov/pubmed/28199214
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