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The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells

High-dose synthetic estrogen therapy was the standard treatment of advanced breast cancer for three decades until the discovery of tamoxifen. A range of substituted triphenylethylene synthetic estrogens and diethylstilbestrol were used. It is now known that low doses of estrogens can cause apoptosis...

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Gepubliceerd in:Mol Pharmacol
Hoofdauteurs: Maximov, Philipp Y., Abderrahman, Balkees, Hawsawi, Yousef M., Chen, Yue, Foulds, Charles E., Jain, Antrix, Malovannaya, Anna, Fan, Ping, Curpan, Ramona F., Han, Ross, Fanning, Sean W., Broom, Bradley M., Quintana Rincon, Daniela M., Greenland, Jeffery A., Greene, Geoffrey L., Jordan, V. Craig
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2020
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294906/
https://ncbi.nlm.nih.gov/pubmed/32362585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119776
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