The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells

High-dose synthetic estrogen therapy was the standard treatment of advanced breast cancer for three decades until the discovery of tamoxifen. A range of substituted triphenylethylene synthetic estrogens and diethylstilbestrol were used. It is now known that low doses of estrogens can cause apoptosis...

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Publicado no:Mol Pharmacol
Main Authors: Maximov, Philipp Y., Abderrahman, Balkees, Hawsawi, Yousef M., Chen, Yue, Foulds, Charles E., Jain, Antrix, Malovannaya, Anna, Fan, Ping, Curpan, Ramona F., Han, Ross, Fanning, Sean W., Broom, Bradley M., Quintana Rincon, Daniela M., Greenland, Jeffery A., Greene, Geoffrey L., Jordan, V. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294906/
https://ncbi.nlm.nih.gov/pubmed/32362585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119776
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