Caenorhabditis elegans Lipin 1 moderates the lifespan‐shortening effects of dietary glucose by maintaining ω‐6 polyunsaturated fatty acids

Excessive glucose causes various diseases and decreases lifespan by altering metabolic processes, but underlying mechanisms remain incompletely understood. Here, we show that Lipin 1/LPIN‐1, a phosphatidic acid phosphatase and a putative transcriptional coregulator, prevents life‐shortening effects...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Jung, Yoonji, Kwon, Sujeong, Ham, Seokjin, Lee, Dongyeop, Park, Hae‐Eun H., Yamaoka, Yasuyo, Jeong, Dae‐Eun, Artan, Murat, Altintas, Ozlem, Park, Sangsoon, Hwang, Wooseon, Lee, Yujin, Son, Heehwa G., An, Seon Woo A., Kim, Eun Ji E., Seo, Mihwa, Lee, Seung‐Jae V.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294780/
https://ncbi.nlm.nih.gov/pubmed/32475074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13150
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires