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Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay

The thermal shift assay is a robust method of discovering protein–ligand interactions by measuring the alterations in protein thermal stability under various conditions. Several thermal shift assays have been developed and their throughput has been advanced greatly by the rapid progress in tandem ma...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Principais autores: Li, Jiaming, Van Vranken, Jonathan G., Paulo, Joao A., Huttlin, Edward L., Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294736/
https://ncbi.nlm.nih.gov/pubmed/32243163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00063
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