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FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies
The IgG Fc domain has the capacity to interact with diverse types of receptors, including the neonatal Fc receptor (FcRn) and Fcγ receptors (FcγRs), which confer pleiotropic biological activities. Whereas FcRn regulates IgG epithelial transport and recycling, Fc effector activities, such as antibody...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293622/ https://ncbi.nlm.nih.gov/pubmed/32461366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004325117 |
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