FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies

The IgG Fc domain has the capacity to interact with diverse types of receptors, including the neonatal Fc receptor (FcRn) and Fcγ receptors (FcγRs), which confer pleiotropic biological activities. Whereas FcRn regulates IgG epithelial transport and recycling, Fc effector activities, such as antibody...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Borghi, Sara, Bournazos, Stylianos, Thulin, Natalie K., Li, Chao, Gajewski, Anna, Sherwood, Robert W., Zhang, Sheng, Harris, Eva, Jagannathan, Prasanna, Wang, Lai-Xi, Ravetch, Jeffrey V., Wang, Taia T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293622/
https://ncbi.nlm.nih.gov/pubmed/32461366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004325117
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