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Use of Normalized Prediction Distribution Errors for Assessing Population Physiologically-Based Pharmacokinetic Model Adequacy
Currently employed methods for qualifying population physiologically-based pharmacokinetic (Pop-PBPK) model predictions of continuous outcomes (e.g., concentration-time data) fail to account for within-subject correlations and the presence of residual error. In this study, we propose a new method fo...
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| Publicat a: | J Pharmacokinet Pharmacodyn |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293575/ https://ncbi.nlm.nih.gov/pubmed/32323049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-020-09684-2 |
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