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RNF8 has both KU-dependent and independent roles in chromosomal break repair
Chromosomal double strand breaks (DSBs) can initiate several signaling events, such as ubiquitination, however the precise influence of such signaling on DSB repair outcomes remains poorly understood. With an RNA interference screen, we found that the E3 ubiquitin ligase RNF8 suppresses a deletion r...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293022/ https://ncbi.nlm.nih.gov/pubmed/32427332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa380 |
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