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RNF8 has both KU-dependent and independent roles in chromosomal break repair
Chromosomal double strand breaks (DSBs) can initiate several signaling events, such as ubiquitination, however the precise influence of such signaling on DSB repair outcomes remains poorly understood. With an RNA interference screen, we found that the E3 ubiquitin ligase RNF8 suppresses a deletion r...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293022/ https://ncbi.nlm.nih.gov/pubmed/32427332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa380 |
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