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BLM has Contrary Effects on Repeat-Mediated Deletions, based on the Distance of DNA DSBs to a Repeat and Repeat Divergence

Repeat-mediated deletions (RMDs) often involve repetitive elements (e.g., short interspersed elements) with sequence divergence that is separated by several kilobase pairs (kbps). We have examined RMDs induced by DNA double-strand breaks (DSBs) under varying conditions of repeat sequence divergence...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Mendez-Dorantes, Carlos, Tsai, L. Jillianne, Jahanshir, Eva, Lopezcolorado, Felicia Wednesday, Stark, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085117/
https://ncbi.nlm.nih.gov/pubmed/32023454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.001
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