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Comprehensive behavioral analysis of tryptophan 2,3‐dioxygenase (Tdo2) knockout mice
AIMS: Tryptophan 2,3‐dioxygenase (TDO2) is an initial rate‐limiting enzyme of the kynurenine (Kyn) pathway in tryptophan (Trp) metabolism. The Trp‐degrading enzymes, TDO2 and indoleamine 2,3‐dioxygenase, are activated by stress and/or inflammation. Dysregulation of Trp metabolism, which causes shift...
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| Publicado no: | Neuropsychopharmacol Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7292271/ https://ncbi.nlm.nih.gov/pubmed/30106261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12006 |
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