Comprehensive behavioral analysis of heterozygous Syngap1 knockout mice

AIMS: Synaptic Ras GTPase‐activating protein 1 (SYNGAP1) regulates synaptic plasticity through AMPA receptor trafficking. SYNGAP1 mutations have been found in human patients with intellectual disability (ID) and autism spectrum disorder (ASD). Almost every individual with SYNGAP1‐related ID develops...

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Publicado en:Neuropsychopharmacol Rep
Main Authors: Nakajima, Ryuichi, Takao, Keizo, Hattori, Satoko, Shoji, Hirotaka, Komiyama, Noboru H., Grant, Seth G. N., Miyakawa, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292322/
https://ncbi.nlm.nih.gov/pubmed/31323176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12073
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