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Comprehensive behavioral analysis of indoleamine 2,3‐dioxygenase knockout mice
AIM: Indoleamine 2,3‐dioxygenase 1 (IDO1) metabolizes the essential amino acid tryptophan into kynurenine derivatives, which are involved in neural activity via the kynurenine pathway (KP). IDO1 is an initial rate‐limiting enzyme in the KP and is activated by stress and/or inflammation. The perturba...
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| Veröffentlicht in: | Neuropsychopharmacol Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7292290/ https://ncbi.nlm.nih.gov/pubmed/30175526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12019 |
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