Tryptophan-Restriction Diets Help to Maintain L-Tryptophan Homeostasis in Tryptophan 2,3-Dioxygenase Knockout Mice

We hypothesized that the requirements of essential nutrients are dependent upon catabolic abilities. Mice lacking L-tryptophan 2,3-dioxygenase (TDO) are available. The body concentration of L-tryptophan (L-Trp) has been reported to be higher in TDO-deficient mice than in wild-type (WT) mice. We exam...

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Hauptverfasser: Maeta, Akihiro, Fukuwatari, Tsutomu, Funakoshi, Hiroshi, Nakamura, Toshikazu, Shibata, Katsumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Libertas Academica 2013
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729280/
https://ncbi.nlm.nih.gov/pubmed/23922503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IJTR.S12206
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