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Modulation of Tryptophan Metabolism, Pomotion of Neurogenesis and Alteration of Anxiety-Related Behavior in Tryptophan 2,3-Dioxygenase-Deficient Mice

Although tryptophan (Trp) and its metabolites, such as serotonin (5-HT) and kynurenines (KYNs), are strong modulators of emotional behavior, the metabolic pathway(s) responsible for this physiological modulation is not fully understood. Two of the initial rate-limiting enzymes of the kynurenine path...

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Detalhes bibliográficos
Main Authors: Funakoshi, Hiroshi, Kanai, Masaaki, Nakamura, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195223/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IJTR.S5783
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