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Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

The Src family kinases (SFKs) Src, Lyn, and Fyn are essential for platelet activation and also involved in megakaryocyte (MK) development and platelet production. Platelet SFKs are inhibited by C-terminal Src kinase (Csk), which phosphorylates a conserved tyrosine in their C-terminal tail, and are a...

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Foilsithe in:Blood
Main Authors: Nagy, Zoltan, Mori, Jun, Ivanova, Vanesa-Sindi, Mazharian, Alexandra, Senis, Yotis A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291955/
https://ncbi.nlm.nih.gov/pubmed/32016283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002848
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