Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug

The insulin-like growth factor (IGF)-axis was implicated in cancer progression and identified as a clinically important therapeutic target. Several IGF-I receptor (IGF-IR) targeting drugs including humanized monoclonal antibodies have advanced to phase II/III clinical trials, but to date, have not p...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Chen, Yinhsuan Michely, Qi, Shu, Perrino, Stephanie, Hashimoto, Masakazu, Brodt, Pnina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290707/
https://ncbi.nlm.nih.gov/pubmed/32365498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051098
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