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Therapeutic Targeting of the IGF Axis

The insulin like growth factor (IGF) axis plays a fundamental role in normal growth and development, and when deregulated makes an important contribution to disease. Here, we review the functions mediated by ligand-induced IGF axis activation, and discuss the evidence for the involvement of IGF sign...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Osher, Eliot, Macaulay, Valentine M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721736/
https://ncbi.nlm.nih.gov/pubmed/31416218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080895
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