Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases

Liver metastases (LM) remain a major cause of cancer-associated death and a clinical challenge. Here we explore a sexual dimorphism observed in the regulation of the tumor immune microenvironment (TIME) of LM, wherein the accumulation of myeloid-derived suppressor cells (MDSC) and regulatory T cells...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Milette, Simon, Hashimoto, Masakazu, Perrino, Stephanie, Qi, Shu, Chen, Michely, Ham, Boram, Wang, Ni, Istomine, Roman, Lowy, Andrew M., Piccirillo, Ciriaco A., Brodt, Pnina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917725/
https://ncbi.nlm.nih.gov/pubmed/31848339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13571-x
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