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Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells

Triple negative breast cancer (TNBC) is associated with unfavorable prognosis and high relapse rates following chemotherapy. There is an urgent need to develop effective targeted therapy for this BC subtype. The type I insulin-like growth factor receptor (IGF-IR) was identified as a potential target...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Tsui, Jennifer, Qi, Shu, Perrino, Stephanie, Leibovitch, Matthew, Brodt, Pnina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065809/
https://ncbi.nlm.nih.gov/pubmed/33916323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040527
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