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Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells

Triple negative breast cancer (TNBC) is associated with unfavorable prognosis and high relapse rates following chemotherapy. There is an urgent need to develop effective targeted therapy for this BC subtype. The type I insulin-like growth factor receptor (IGF-IR) was identified as a potential target...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Tsui, Jennifer, Qi, Shu, Perrino, Stephanie, Leibovitch, Matthew, Brodt, Pnina
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065809/
https://ncbi.nlm.nih.gov/pubmed/33916323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040527
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