Tubulin Resists Degradation by Cereblon-Recruiting PROTACs

Dysregulation of microtubules and tubulin homeostasis has been linked to developmental disorders, neurodegenerative diseases, and cancer. In general, both microtubule-stabilizing and destabilizing agents have been powerful tools for studies of microtubule cytoskeleton and as clinical agents in oncol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cells
Prif Awduron: Gasic, Ivana, Groendyke, Brian J., Nowak, Radosław P., Yuan, J. Christine, Kalabathula, Joann, Fischer, Eric S., Gray, Nathanael S., Mitchison, Timothy J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290497/
https://ncbi.nlm.nih.gov/pubmed/32349222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051083
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