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TTC5 mediates autoregulation of tubulin via mRNA degradation
Tubulins play crucial roles in cell division, intracellular traffic, and cell shape. Tubulin concentration is autoregulated by feedback control of mRNA degradation via an unknown mechanism. Here, we identified tetratricopeptide protein 5 (TTC5) as a tubulin-specific ribosome-associating factor that...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942541/ https://ncbi.nlm.nih.gov/pubmed/31727855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz4352 |
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