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FoxO suppresses endoplasmic reticulum stress to inhibit growth of Tsc1-deficient tissues under nutrient restriction

The transcription factor FoxO has been shown to block proliferation and progression in mTORC1-driven tumorigenesis but the picture of the relevant FoxO target genes remains incomplete. Here, we employed RNA-seq profiling on single clones isolated using laser capture microdissection from Drosophila l...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Gupta, Avantika, Stocker, Hugo
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289595/
https://ncbi.nlm.nih.gov/pubmed/32525804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53159
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