Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability

Histone deacetylases (HDACs) are evolutionary conserved enzymes which operate by removing acetyl groups from histones and other protein regulatory factors, with functional consequences on chromatin remodeling and gene expression profiles. We provide here a review on the recent knowledge accrued on t...

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Vydáno v:Genes (Basel)
Hlavní autoři: Milazzo, Giorgio, Mercatelli, Daniele, Di Muzio, Giulia, Triboli, Luca, De Rosa, Piergiuseppe, Perini, Giovanni, Giorgi, Federico M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288346/
https://ncbi.nlm.nih.gov/pubmed/32429325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11050556
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