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The role of histone deacetylases (HDACs) in human cancer

The balance of histone acetylation and deacetylation is an epigenetic layer with a critical role in the regulation of gene expression. Histone acetylation induced by histone acetyl transferases (HATs) is associated with gene transcription, while histone hypoacetylation induced by histone deacetylase...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Ropero, Santiago, Esteller, Manel
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543853/
https://ncbi.nlm.nih.gov/pubmed/19383284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2007.01.001
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