The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice

An important epigenetic modification in Huntington’s disease (HD) research is histone acetylation, which is regulated by histone acetyltransferase and histone deacetylase (HDAC) enzymes. HDAC inhibitors have proven effective in HD model systems, and recent work is now focused on functional dissectio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jia, Haiqun, Wang, Ying, Morris, Charles D., Jacques, Vincent, Gottesfeld, Joel M., Rusche, James R., Thomas, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816519/
https://ncbi.nlm.nih.gov/pubmed/27031333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152498
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