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The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice

An important epigenetic modification in Huntington’s disease (HD) research is histone acetylation, which is regulated by histone acetyltransferase and histone deacetylase (HDAC) enzymes. HDAC inhibitors have proven effective in HD model systems, and recent work is now focused on functional dissectio...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Jia, Haiqun, Wang, Ying, Morris, Charles D., Jacques, Vincent, Gottesfeld, Joel M., Rusche, James R., Thomas, Elizabeth A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816519/
https://ncbi.nlm.nih.gov/pubmed/27031333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152498
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