Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation

Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation. Whether additional mechanisms contribute to β-catenin-driven hyperplasi...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Pignatti, Emanuele, Leng, Sining, Yuchi, Yixing, Borges, Kleiton S., Guagliardo, Nick A., Shah, Manasvi S., Ruiz-Babot, Gerard, Kariyawasam, Dulanjalee, Taketo, Makoto Mark, Miao, Ji, Barrett, Paula Q., Carlone, Diana L., Breault, David T.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281829/
https://ncbi.nlm.nih.gov/pubmed/32320669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107524
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