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Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation. Whether additional mechanisms contribute to β-catenin-driven hyperplasi...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7281829/ https://ncbi.nlm.nih.gov/pubmed/32320669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107524 |
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