The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms

The glucocorticoid (GC) rhythm is entrained to light-dark (LD) cycles via a molecular clock in the suprachiasmatic nucleus (SCN) and is maintained by an adrenal clock synchronized by SCN-dependent signals. Targeted deletion of the core clock gene Bmal1 can disrupt adrenal clock function. The require...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Engeland, William C, Massman, Logan, Mishra, Shubhendu, Yoder, J Marina, Leng, Sining, Pignatti, Emanuele, Piper, Mary E, Carlone, Diana L, Breault, David T, Kofuji, Paulo
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240903/
https://ncbi.nlm.nih.gov/pubmed/30321360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00769
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