Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice

The circadian glucocorticoid (GC) rhythm is dependent on a molecular clock in the suprachiasmatic nucleus (SCN) and an adrenal clock that is synchronized by the SCN. To determine whether the adrenal clock modulates GC responses to stress, experiments used female and male Cyp11A1(Cre/+)::Bmal1(Fl/Fl)...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Engeland, William C, Massman, Logan, Miller, Lauren, Leng, Sining, Pignatti, Emanuele, Pantano, Lorena, Carlone, Diana L, Kofuji, Paulo, Breault, David T
Format: Artigo
Language:Inglês
Published: Endocrine Society 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735739/
https://ncbi.nlm.nih.gov/pubmed/31398249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00357
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