Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer

The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in aerobic conditions. Targeting the Warburg effect to specifically deliver sugar conjugated cytotoxic compounds into tumor c...

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Publicado no:Mar Drugs
Main Authors: Dyshlovoy, Sergey A., Pelageev, Dmitry N., Hauschild, Jessica, Sabutskii, Yurii E., Khmelevskaya, Ekaterina A., Krisp, Christoph, Kaune, Moritz, Venz, Simone, Borisova, Ksenia L., Busenbender, Tobias, Denisenko, Vladimir A., Schlüter, Hartmut, Bokemeyer, Carsten, Graefen, Markus, Polonik, Sergey G., Anufriev, Victor Ph., von Amsberg, Gunhild
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281150/
https://ncbi.nlm.nih.gov/pubmed/32403427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18050251
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