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Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest

From a root bark of Lespedeza bicolor Turch we isolated two new (7 and 8) and six previously known compounds (1–6) belonging to the group of prenylated polyphenols. Their structures were elucidated using mass spectrometry, nuclear magnetic resonance and circular dichroism spectroscopy. These natural...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Dyshlovoy, Sergey A., Tarbeeva, Darya, Fedoreyev, Sergey, Busenbender, Tobias, Kaune, Moritz, Veselova, Marina, Kalinovskiy, Anatoliy, Hauschild, Jessica, Grigorchuk, Valeria, Kim, Natalya, Bokemeyer, Carsten, Graefen, Markus, Gorovoy, Petr, von Amsberg, Gunhild
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175281/
https://ncbi.nlm.nih.gov/pubmed/32183314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030451
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