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HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP‐43 proteinopathies

TAR DNA‐binding protein 43 (TDP‐43) has been implicated in frontotemporal lobar degeneration with ubiquitin‐positive inclusions (FTLD‐TDP) and amyotrophic lateral sclerosis. Histone deacetylase 1 (HDAC1) is involved in DNA repair and neuroprotection in numerous neurodegenerative diseases. However, t...

詳細記述

保存先:
書誌詳細
出版年:EMBO Mol Med
主要な著者: Wu, Cheng‐Chun, Jin, Lee‐Way, Wang, I‐Fang, Wei, Wei‐Yen, Ho, Pei‐Chuan, Liu, Yu‐Chih, Tsai, Kuen‐Jer
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278561/
https://ncbi.nlm.nih.gov/pubmed/32449313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910622
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