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Disease Animal Models of TDP-43 Proteinopathy and Their Pre-Clinical Applications

Frontotemperal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are two common neurodegenerative diseases. TDP-43 is considered to be a major disease protein in FTLD/ALS, but it’s exact role in the pathogenesis and the effective treatments remains unknown. To address this question a...

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Detalhes bibliográficos
Main Authors: Liu, Yu-Chih, Chiang, Po-Min, Tsai, Kuen-Jer
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821604/
https://ncbi.nlm.nih.gov/pubmed/24113586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141020079
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