Myt Transcription Factors prevent stress-response gene overactivation to enable postnatal pancreatic β-cell proliferation, function, and survival

Although cellular stress response is important in maintaining function and survival, overactivation of late-stage stress effectors causes dysfunction and death. We show that the Myelin Transcription Factors Myt1 (Nzf2), Myt2 (Myt1l, Nztf1, Png-1), and Myt3 (St18, Nzf3) prevent such overactivation in...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Hu, Ruiying, Walker, Emily, Huang, Chen, Xu, Yanwen, Weng, Chen, Erickson, Gillian E., Golovin, Anastasia, Yang, Xiaodun, Brissova, Marcella, Kaverina, Irina, Appakalai, Balamurugan N., Wright, Christopher V. E., Li, Yan, Stein, Roland, Gu, Guoqiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278035/
https://ncbi.nlm.nih.gov/pubmed/32359405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.04.003
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