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Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation
High levels of Ngn3 expression in pancreatic progenitor cells are both necessary and sufficient to initiate endocrine differentiation. While it is clear that the Notch-Hes1-mediated signals control the number of Ngn3-expressing cells in the developing pancreas, it is not known what factors control t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423199/ https://ncbi.nlm.nih.gov/pubmed/18394599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.052 |
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