Slow Death of Postnatal Hippocampal Neurons by GABA(A) Receptor Overactivation

Neurotransmitters can have both toxic and trophic functions in addition to their role in neural signaling. Surprisingly, chronic blockade of GABA(A) receptor activity for 5–8 d in vitro enhanced survival of hippocampal neurons, suggesting that GABA(A) receptor overactivation may be neurotoxic. Poten...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Xu, Wanyan, Cormier, Robert, Fu, Tao, Covey, Douglas F., Isenberg, Keith E., Zorumski, Charles F., Mennerick, Steven
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
Fag:
ARTICLE
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773103/
https://ncbi.nlm.nih.gov/pubmed/10777778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03147.2000
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