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Slow Death of Postnatal Hippocampal Neurons by GABA(A) Receptor Overactivation

Neurotransmitters can have both toxic and trophic functions in addition to their role in neural signaling. Surprisingly, chronic blockade of GABA(A) receptor activity for 5–8 d in vitro enhanced survival of hippocampal neurons, suggesting that GABA(A) receptor overactivation may be neurotoxic. Poten...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Xu, Wanyan, Cormier, Robert, Fu, Tao, Covey, Douglas F., Isenberg, Keith E., Zorumski, Charles F., Mennerick, Steven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773103/
https://ncbi.nlm.nih.gov/pubmed/10777778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03147.2000
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