Slow Death of Postnatal Hippocampal Neurons by GABA(A) Receptor Overactivation

Neurotransmitters can have both toxic and trophic functions in addition to their role in neural signaling. Surprisingly, chronic blockade of GABA(A) receptor activity for 5–8 d in vitro enhanced survival of hippocampal neurons, suggesting that GABA(A) receptor overactivation may be neurotoxic. Poten...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Xu, Wanyan, Cormier, Robert, Fu, Tao, Covey, Douglas F., Isenberg, Keith E., Zorumski, Charles F., Mennerick, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773103/
https://ncbi.nlm.nih.gov/pubmed/10777778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03147.2000
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