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Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork
The eukaryotic replisome, organized around the Cdc45-MCM-GINS (CMG) helicase, orchestrates chromosome replication. Multiple factors associate directly with CMG, including Ctf4 and the heterotrimeric fork protection complex (Csm3/Tof1 and Mrc1), which has important roles including aiding normal repli...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7276988/ https://ncbi.nlm.nih.gov/pubmed/32369734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.04.012 |
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