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DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in C. elegans
Assembly of the CDC45-MCM-GINS helicase is the key regulated step during eukaryotic DNA replication initiation. Until now, it was unclear whether metazoa require additional factors not present in yeast. Here we show that Caenorhabditis elegans DNSN-1, the orthologue of human DONSON, functions during...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2023
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615117/ https://ncbi.nlm.nih.gov/pubmed/37590372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.adi4932 |
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