Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium vivax Volunteer Infection Study

Chloroquine has been used for the treatment of malaria for > 70 years; however, chloroquine pharmacokinetic (PK) and pharmacodynamic (PD) profile in Plasmodium vivax malaria is poorly understood. The objective of this study was to describe the PK/PD relationship of chloroquine and its major metab...

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Publicado en:Clin Pharmacol Ther
Autores principales: Abd‐Rahman, Azrin N., Marquart, Louise, Gobeau, Nathalie, Kümmel, Anne, Simpson, Julie A., Chalon, Stephan, Möhrle, Jörg J., McCarthy, James S.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276750/
https://ncbi.nlm.nih.gov/pubmed/32415986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1893
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