Mitral valve leaflet response to ischaemic mitral regurgitation: from gene expression to tissue remodelling

Ischaemic mitral regurgitation (IMR), a frequent complication following myocardial infarction (MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating evidence suggests that mitral valve (MV) leaflets actively remodel post MI, and this remodelling increases both the sev...

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Foilsithe in:J R Soc Interface
Main Authors: Howsmon, Daniel P., Rego, Bruno V., Castillero, Estibaliz, Ayoub, Salma, Khalighi, Amir H., Gorman, Robert C., Gorman, Joseph H., Ferrari, Giovanni, Sacks, Michael S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Royal Society 2020
Ábhair:
Life Sciences–Engineering interface
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276554/
https://ncbi.nlm.nih.gov/pubmed/32370692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0098
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